The San Blas Islands of Panama is an archipelago comprising approximately 365 islands and cays, of which only 49 are inhabited. They lie off the north coast of the Isthmus of Panama, east of the Panama Canal.
Portobelo is a port city and corregimiento in Portobelo District, Colón Province, Panama with a population of 4,559 as of 2010. It is the seat of Portobelo District. It was established during the Spanish colonial period.